Laboratorij za istraživanje boli

Laboratorij za istraživanje boli Medicinskog fakulteta u Splitu namijenjen je istraživanju nocicepcije i boli.

Povijest

Laboratorij za istraživanje boli osnovan je 2002. godine na Medicinskom fakultetu u Splitu. Utemeljitelj Laboratorija je prof. dr. sc. Damir Sapunar. Voditeljica laboratorija je prof. dr. sc. Livia Puljak.

Istraživanja

Laboratorij se bavi istraživanjima neurobiologije neuropatske boli i doživljaja boli.

Objavljeni radovi

• Fisher G et al. Direct injection into the dorsal root ganglion: Technical, behavioral, and histological observations. J Neurosci Methods. 2011.
  
• Kraljevic S et al. Parents' Pain Catastrophizing is Related to Pain Catastrophizing of Their Adult Children. Int J Behav Med. 2012.
  
• Puljak L & Sapunar D. Web-Based Elective Courses for Medical Students: An Example in Pain. Pain Med. 2011.
  
• Sapunar et al. Attenuation of pain-related behavior evoked by injury through blockade of neuropeptide Y Y2 receptor. Pain. 2011.
  
• Lovric Kojundzic et al. Depression of Ca/Calmodulin-Dependent Protein Kinase II in Dorsal Root Ganglion Neurons after Spinal Nerve Ligation. J Comp Neurol 2010.
  
• Puljak L et al. Lidocaine injection into the rat dorsal root ganglion causes neuroinflammation and pain-related behavior. Anesth Analg. 2009.
  
• Kosta V et al. Spine deformity in a rat model of neuropathic pain causes pain-related behavior. Eur J Pain. 2009.
  
• Puljak L et al. Targeted delivery of pharmacological agents into rat dorsal root ganglion. J Neurosci Methods. 2009.
  
• Hogan Q et al. Restoration of calcium influx corrects membrane hyperexcitability in injured rat dorsal root ganglion neurons. Anesth Analg. 2008.
  
• Znaor L et al. Association of neural inflammation with hyperalgesia following spinal nerve ligation, Croat Med J. 2007.
  
• Sapunar D et al. Distinct membrane effects of spinal nerve ligation on injured and adjacent dorsal root ganglion neurons. Anesthesiology 2005.
  
• Sapunar D et al. Effect of peripheral axotomy on pain-related behavior and dorsal root ganglion neurons excitability in NPY transgenic rats. Brain Res 2005.